Module membership and gene significance
WebThis explain why the Module eigengene (1st Principal component) of the turquoise module poorly correlate with the trait 6 (Module-trait relationship table). Perhaps, I … Web10 mei 2024 · Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were performed for the genes in modules with clinical interest. Genes with a significance over 0.2 and a module membership over 0.8 were used as hub genes.
Module membership and gene significance
Did you know?
Web27 feb. 2024 · Fourth, modules were detected using hierarchical clustering and dynamic tree cutting functions. Finally, gene significance (GS) and module membership (MM) correlations were calculated, and the corresponding module gene information was extracted for further analysis.
Web18 mei 2024 · a Scatter plot of the correlation of module membership (correlation coefficients between genes with MEgreen module) and gene significance (correlation coefficients between genes with trait of SZ increase). b Heatmap of MEgreen module genes in two B. rapa accessions, which was displayed based on log 2 (FPKM + 1). Web6 mrt. 2024 · The results of this study showed that the genes of the blue module (cor = 0.62, P = 3.3e-129) have higher importance and a higher module membership than …
Web22 apr. 2024 · We therefore selected the pink model for subsequent analysis. We performed an intramodular analysis for the pink module, and the module membership and gene significance showed a very meaningful correlation (and ), indicating that the 160 genes in the pink module tend to be remarkably correlated with NK cells resting infiltration level … Web27 aug. 2024 · Mechanically, the potential regulators of blue module were investigated. These findings highlight an important role of the blue module and its affiliated genes in …
Web10 mei 2024 · Genes with a significance over 0.2 and a module membership over 0.8 were used as hub genes. Subsequently, we screened these hub genes in the published …
Web10 jun. 2024 · Combining the identified WGCNA modules to meta-modules and subsequent analysis of this meta-modules demonstrated a high correlation with HD (correlation r = 0.5, p-value = 1e-38), a positive correlation between gene significance and module membership of 0.73 (p-value = 2e-54), and the highest mean gene … top rated inkless pocket printerWeb6 mrt. 2024 · Finally, we used the overlapping data to identify hub genes. out of a total of 12 identified modules by WGCNA, the blue module was find to have the most statistically significant correlation with prednisolone resistance and Nine genes including SOD1, CD82, FLT3, GART, HPRT1, ITSN1, TIAM1, MRPS6, MYC were recognized as hub genes … top rated inkjet single function printersWebDownload scientific diagram Correlations between gene module memberships and gene significance for the modules associated with clinical traits. from publication: Gene Co-expression Networks Are ... top rated inline skates 2015Web9 feb. 2024 · Module membership (MM) and gene significance (GS) revealed the correlation between the gene expression and infiltrated immune cell abundance. Genes in modules that were highly associated with infiltrated immune cells (correlation ≥ 0.7 and p value ≤ 0.05) were extracted for further study (GS ≥ 0.5 and MM ≥ 0.5). top rated inkjet printers 2023Web7 jul. 2024 · Gene significance (GS) was the correlation coefficient between the expression value of a gene and a phenotype, representing the association between genes and … top rated innerspring mattresses 2017Web26 sep. 2024 · Genes in modules with significant module-trait associations (coefficient > 0.65 and p value < 0.001) were included in functional enrichment analysis. Hub gene … top rated inner tubes for boatingWeb10 apr. 2024 · We constructed a protein-protein interaction network from DEGs followed by network clustering. Members of the two most extensive modules went under the enrichment analysis. We introduced a number of hub genes and gene families playing essential roles in oncogenic pathways and the pathogenesis of gastric cancer. top rated innerspring crib mattresses