Ctcf is a barrier for 2c-like reprogramming
WebCTCF is a Barrier for Totipotent-like Reprogramming Relations BioProject PRJNA693454 SRA SRP302520 Supplementary file Size Download File type/resource … WebNov 15, 2024 · In line with CTCF acting as a barrier to conversion, the lost expression of this critical chromatin regulator in ESCs eased their spontaneous and asynchronous …
Ctcf is a barrier for 2c-like reprogramming
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WebHere, we show that the CCCTC-binding factor (CTCF) is a barrier for 2C-like reprogramming. Indeed, forced conversion to a 2C-like state by the transcription factor DUX is associated with DNA damage at a subset of CTCF binding sites. Depletion of CTCF in ESC efficiently promotes spontaneous and asynchronous conversion to a 2C-like … WebDec 20, 2024 · Here, we show that CTCF is a barrier for 29 2C-like reprogramming. Indeed, forced conversion to a 2C-like state by DUX expression was 30 associated with …
WebMany attempts have been made to induce high-quality embryonic stem cells such as pluripotent stem cells and totipotent stem cells, but challenges remain to be overcome such as appropriate methods and sources. Demethylation of the genome after WebCTCF is a barrier for 2C-like reprogramming. T Olbrich, M Vega-Sendino, D Tillo, W Wu, N Zolnerowich, R Pavani, ... Nature Communications 12 (1), 4856, 2024. 28: 2024: Methylated cytosines mutate to transcription factor …
WebFeb 17, 2016 · The observed latency and low efficiency of induced pluripotent stem cell generation during direct reprogramming reflect epigenetic barriers that are imposed during differentiation. Once these... WebAug 11, 2024 · Europe PMC is an archive of life sciences journal literature.
WebAug 22, 2024 · Olbrich T, Vega-Sendino M, Tillo D, Wu W, Zolnerowich N, Pavani R, Tran AD, Domingo CN, Franco M, Markiewicz-Potoczny M et al (2024) CTCF is a barrier for 2C-like reprogramming. Nature Communications 12: 4856 Crossref CAS PubMed Web of Science® Google Scholar
WebMar 19, 2024 · CTCF is a barrier for 2C-like reprogramming. Interplay between CTCF boundaries and a super enhancer controls cohesin extrusion trajectories and gene … chinese lantern festival in caryWebAug 3, 2015 · In the comparison of p60KD-induced 2C–like cells: with zygote p=1; with 2-cell p=2.092e-13; with 4-cell p=0.051; with 8-cell p=1; with 16-cell p=1; with early blastocyst p=1. In the comparison of... chinese lantern festival durhamWebSep 7, 2024 · CTCF is a Barrier for Totipotent-like Reprogramming. Organism. Mus musculus. Experiment type. Genome binding/occupancy profiling by high throughput sequencing. Other. Summary. This SuperSeries is composed of the SubSeries listed below. chinese lantern festival philadelphia couponWebAug 11, 2024 · CTCF is a barrier for 2C-like reprogramming DOI: 10.1038/s41467-021-25072-x License Authors: Teresa Olbrich Maria Vega-Sendino Desiree Tillo Wei Wu … grandpappy\\u0027s furniture chilliwack bcWebOct 26, 2024 · Under serum/leukemia inhibitory factor (LIF) culture conditions, around 1%–2% of mouse embryonic stem cells (mESCs) were found to exhibit transcription features such as the 2C embryos and were known as 2C-like embryonic stem cells (2CLCs) ( Macfarlan et al., 2012; Li and Izpisua Belmonte, 2024 ). 2CLCs possess the ability to … grand pappy\u0027s furniture chilliwackWebAug 11, 2024 · Depletion of CTCF in ESC efficiently promotes spontaneous and asynchronous conversion to a 2C-like state and is reversible upon restoration of CTCF … grand pappy\\u0027s furniture chilliwackWebApr 6, 2024 · Here, we show that the histone chaperone RBBP4 acts as a powerful barrier by regulating heterochromatin assembly for reprogramming of the pluripotent state toward the totipotent 2C-like state. RBBP4 recruits different epigenetic factors to distinct TEs and modulates chromatin compaction through chromatin remodelers. chinese lantern festival los angeles