Citrate transporter family protein

Author: jcwp

August undefined, 2024

WebThe citrate carrier (CiC), a nuclear-encoded protein located in the mitochondrial inner membrane, is a member of the mitochondrial carrier family. CiC plays an important role … WebSLC13A5. Solute carrier family 13 (sodium-dependent citrate transporter), member 5 also known as the Na+/citrate cotransporter or mIndy is a protein that in humans is encoded by the SLC13A5 gene. [5] It is the mammalian homolog of the fly Indy gene .

Slc25a1 solute carrier family 25 member 1 [ (Norway rat)]

WebFeb 23, 2024 · The small molecule citrate is a key molecule that is synthesized de novo and involved in diverse biochemical pathways influencing cell metabolism and function. Citrate is highly abundant in the circulation, and cells take up extracellular citrate via the sodium-dependent plasma membrane transporter NaCT encoded by the SLC13A5 gene. … WebSLC25 is the largest solute transporter family in humans. 53 members have been ... (SLC25A1, or citrate transport protein; TC# 2.A.29.7.2) Graves disease carrier protein … portadown people\\u0027s park

Tricarboxylate Citrate Transporter of an Oleaginous Fungus

WebApr 13, 2024 · The inhibited key enzymes in the citrate cycle highlighted inactive energy ... WU75_10380, WU75_10390, and WU75_10385), encoding a choline ABC transporter ATP-binding protein, a choline ABC transporter substrate-binding protein ... transporter periplasmic adaptor subunit and a multidrug transporter. The RND family efflux pumps ... WebWe have characterized a nodule-specific citrate transporter of the multidrug and toxic compound extrusion family, MtMATE67 of Medicago truncatula The MtMATE67 gene was induced early during nodule development and expressed primarily in the invasion zone of mature nodules. The MtMATE67 protein was localized to the plasma membrane of … WebCitrate transporter family protein Imported. Gene names. Ordered locus names. PFL_2499 Imported. Organism names. Organism. Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) Imported. Taxonomic … portadown oil supplies craigavon

Structure and elevator mechanism of the Na+-citrate transporter …

Molecular Mechanism of Citrate Efflux by the …

WebJul 1, 2007 · The cellular transport of long-chain fatty acids (LCFAs) across the plasma membrane has long been thought to occur via passive diffusion. However, in recent years a substantial body of literature has emerged indicating that LCFA uptake into muscle cells occurs via a protein-mediated process (for review see Bonen et al. 2002; Luiken et al. … WebLiver cells import citrate through the sodium-dependent citrate transporter NaCT (encoded by SLC13A5) and, as a consequence, this protein is a potential target for anti-obesity drugs. Here, to understand the structural basis of its inhibition mechanism, we determined cryo-electron microscopy structures of human NaCT in complexes with citrate or ... portadown orange hallWebOct 29, 2024 · Summary. This gene encodes a member of the mitochondrial carrier family. The encoded protein is responsible for the movement of tricarboxylates, such as citrate, across the inner mitochondrial membrane. It is essential to the bioenergetics of hepatic cells, supplying the cytoplasm with a carbon source for fatty acid and sterol biosynthesis, and ... portadown parish

"WebThe partially compromised nodule functioning induces two striking phenotypes: anthocyanin accumulation already displayed 4 weeks after inoculation and shoot biomass deficiency, which is detected by long-term phenotyping. LjNPF8.6 achieves nitrate uptake in Xenopus laevis oocytes at both 0.5 and 30 mm external concentrations, and a possible role ... " - Citrate transporter family protein

Citrate transporter family protein

Fatty acid binding protein facilitates sarcolemmal fatty acid transport …

WebLiver cells import citrate through the sodium-dependent citrate transporter NaCT (encoded by SLC13A5) and, as a consequence, this protein is a potential target for anti-obesity … WebJan 20, 2024 · Moreover, mutations of a member of the citrate transporter family in fruit fly, INDY, promote longevity, ... Inhibitors of the mitochondrial citrate transport protein: validation of the role of ...

Did you know?

WebFeb 17, 2024 · Liver cells import citrate through the sodium-dependent citrate transporter NaCT (encoded by SLC13A5) and, as a consequence, this protein is a potential target for anti-obesity drugs. Websolute carrier family 20 (mitochondrial citrate transporter), member 3; solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1; ... Iacobazzi V, Lauria G, …

WebThis gene encodes a member of the mitochondrial carrier subfamily of solute carrier proteins. Members of this family include nuclear-encoded transporters that translocate … WebNov 14, 2008 · Recently, three studies have reported that some MATE proteins are involved in the transport of citrate, which is required for iron (Fe) translocation or …

WebMar 21, 2024 · This gene encodes a protein belonging to the solute carrier family 13 group of proteins. This family member is a sodium-dependent citrate cotransporter that may … WebCitrate plays a pivotal role not only in the generation of metabolic energy but also in the synthesis of fatty acids, isoprenoids, and cholesterol in mammalian cells. Plasma levels …

WebDec 15, 2024 · Iacobazzi et al. (1997) determined that the open reading frame of the human citrate transporter gene encodes a mature protein of 298 amino acids and a …

WebAug 1, 2024 · The recently determined crystal structure of the bacterial Na +-citrate symporter CitS provides unexpected structural and mechanistic insights. The protein has a fold that has not been seen in other proteins, but the oligomeric state, domain organization and proposed transport mechanism strongly resemble those of the sodium … portadown phone repairsWebSep 29, 2012 · The 2-oxoglutarate carrier (OGC) belongs to the mitochondrial carrier protein family whose members are responsible for the exchange of metabolites, cofactors and nucleotides between the cytoplasm and mitochondrial matrix. Initially, OGC was characterized by determining substrate specificity, kinetic parameters of transport, … portadown police facebookWebMar 1, 2024 · The Mitochondrial Carrier Family. With 53 members, the mitochondrial carrier family (solute carrier family 25, SLC25) is the largest solute transporter family in humans. They transport solutes across the impermeable inner membrane of mitochondria for important cellular processes, such as oxidative phosphorylation of fats and sugars, … portadown orange districtWebApr 7, 2024 · The TaALMT1 gene has been found to belong to a new transporter family and regulates the selective efflux of malate. ... and sorghum [48], and its homologue were then identified as OsFRDL4 (a MATE family citrate transporter) in rice [49 ... (OsSTAR1/2, encodes an ABC transporter protein that forms a complex to regulate the efflux of UDP … portadown northern irelandWebAbstract. Citrate, an organic trivalent anion, is a major substrate for generation of energy in most cells. It is produced in mitochondria and used either in the Krebs' cycle or released … portadown people\u0027s parkWebAluminum-activated malate transporter 1. Gene. ALMT1. Status. UniProtKB reviewed (Swiss-Prot) ... Al tolerance QTL also found on chromosome 1. Acts in parallel but independently of MATE, an aluminum-activated root citrate transporter. ... Protein family/group databases. TCDB. 2.A.85.2.3 the aromatic acid exporter (arae) family; … portadown on mapWebet al., 2004). Functional gene variants of transport proteins are involved in human diseases, and about 10% of established T2D loci are related to membrane transporters. II. Solute Carrier Membrane Transport Proteins Solute carrier (SLC) proteins are a group of trans-membrane transporters that mediate solute influx portadown planning portal