Cimetidine and theophylline drug interaction
WebAfter intravenous administration of cimetidine, the majority of the parent drug (58-77%) is eliminated unchanged in the urine. 2,7 Cimetidine’s primary metabolite is cimetidine sulfoxide and represents an estimated … WebMar 22, 2024 · Drug-Drug Interactions: Theophylline interacts with a wide variety of drugs. The interaction may be pharmacodynamic, i.e. alterations in the therapeutic response to theophylline or another drug or occurrence of adverse effects without a change in serum theophylline concentration. ... Cimetidine. Decreases theophylline …
Cimetidine and theophylline drug interaction
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WebThere are 7 disease interactions with theophylline which include: PUD renal dysfunction seizure disorders GERD hemodialysis reduced clearance tachyarrhythmias Report … WebAug 25, 2024 · Severe interactions of cimetidine include: astemizole; cisapride; dofetilide; eliglustat; lomitapide; pimozide; terfenadine; Cimetidine has serious interactions with at …
WebSearch for drug interactions with our API. Drug Allergy. ... non-bronchodilator prophylactic effects). Mechanism of action. Theophylline relaxes the smooth muscle of the bronchial airways and pulmonary … WebThe effects of cimetidine on the pharmacokinetics of theophylline were studied in seven healthy subjects at steady state after oral dosing. Aminophylline (200 mg) was …
WebIn summary, cimetidine is a potent inhibitor of liver microsomal activity, which may also decrease hepatic blood flow. Other effects of the drug include inhibition of gastric secretion and intrinsic toxic properties. These effects, combined with the common use of cimetidine in clinical practice, make the risk of adverse drug interactions a ... WebInfluences of cimetidine dose and age on the cimetidine-theophylline interaction were evaluated. Group Y consisted of nine young adults, aged 22–35 years, and Group …
WebTheophylline is used to treat lung diseases such as asthma and COPD ( bronchitis, emphysema ). It must be used regularly to prevent wheezing and shortness of breath. This medication belongs to a ...
WebMar 1, 1983 · The effects of cimetidine on the pharmacokinetics of theophylline were studied in seven healthy subjects at steady state after oral dosing. Aminophylline (200 mg) was administered every six hours ... derogatory terms for french canadiansWebWebMD provides information about interactions between THSC Cimetidine Oral and cimetidine-theophylline-derivatives. derogatory terms for policeWebDec 13, 2012 · Clinically important interactions are predominantly manifested in those drugs which have a narrow therapeutic index (e.g. Phenytoin, warfarin, theophylline). The interaction leads to higher steady-state blood concentrations and hence increases the incidence of side effects and toxicity. Adverse effects of such interactions can be … chr toyota sport redWebInfluences of cimetidine dose and age on the cimetidine-theophylline interaction were evaluated. Group Y consisted of nine young adults, aged 22–35 years, and Group O of nine elderly adults, aged 60–74 years. Each subject completed three study phases in this randomized crossover study. During Phase A, oral dosing of 5 mg/kg theophylline was ... derogatory terms for californiansWebPhenytoin increases theophylline clearance by increasing microsomal enzyme activity: Serum theophylline and phenytoin concentrations decrease about 40 percent: … derogatory terms for mental healthWebFeb 1, 1983 · The effects of cimetidine on the pharmacokinetics of theophylline were studied in seven healthy subjects at steady state after oral dosing. Aminophylline (200 mg) was administered every six hours for three days (AX then aminophylline (200 mg) and cimetidine (300 mg) were administered every six hours for seven days (A-CX Multiple … derogatory terms for old peopleWebTheophylline comes as an extended-release (long-acting) tablet, extended-release capsule, and a solution (liquid) to take by mouth. It usually is taken every 6, 8, 12, or 24 hours. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. derogatory terms for chinese